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Staff Profiles

Dr Emma Holian

BSc, PhD

Contact Details

Lecturer Above The Bar
------------------------
ADB-G011
Áras De Brún
School of Mathematics, Statistics and Applied Mathematics

T: Ext. 5490
E: emma.holian@nuigalway.ie
 
researcher

Biography

2008 -  Lecturer in Statistics, National University of Ireland, Galway.

2007-2008       Lecturer in Statistics (Contract), University of Limerick, Ireland.

2007   Post-Doc Research Fellow in Statistical Modelling, University of Limerick, Ireland.

2006   Lecturer (Contract), National University of Ireland, Galway.

2006  Research Assistant National Diagnostics Centre, NUI Galway.

2002 - 2006   Ph.D. Statistics, NUI Galway. Embark Initiative IRCSET research scholarship.

1998 - 1999   Actuarial Trainee, Eagle Star Life.

1995-1998  B.Sc. Mathematical Sciences, NUI Galway
 

 
 
 

Research Interests

Research Projects

  Project Start Date End Date
CLUSTER ANALYSIS MXT GLMM E HOLIAN 01-APR-09 28-MAY-12

Peer Reviewed Journals

  Year Publication
(2017) 'Differential impact of hormone receptor status on survival and recurrence for HER2 receptor-positive breast cancers treated with Trastuzumab'
McGuire, A,Kalinina, O,Holian, E,Curran, C,Malone, CA,McLaughlin, R,Lowery, A,Brown, JAL,Kerin, MJ (2017) 'Differential impact of hormone receptor status on survival and recurrence for HER2 receptor-positive breast cancers treated with Trastuzumab'. Breast Cancer Research And Treatment, 164 :221-229 [DOI] [Details]
(2017) 'Screening of exosomal microRNAs from colorectal cancer cells'
Clancy C, Khan S, Glynn CL, Holian E, Dockery P, Lalor P, Brown JA, Joyce MR, Kerin MJ, Dwyer RM. (2017) 'Screening of exosomal microRNAs from colorectal cancer cells'. Cancer Biomarkers, 17 (4):427-435 [DOI] [Details]
(2016) 'Screening of exosomal microRNAs from colorectal cancer cells'
Clancy, C.,Khan, S.,Glynn, C. L.,Holian, E.,Dockery, P.,Lalor, P.,Brown, J. A.,Joyce, M. R.,Kerin, M. J.,Dwyer, R. M. (2016) 'Screening of exosomal microRNAs from colorectal cancer cells'. Cancer Biomark, 17 (44):427-435 [Details]
(2016) 'Screening of exosomal microRNAs from colorectal cancer cells'
Clancy, C,Khan, S,Glynn, CL,Holian, E,Dockery, P,Lalor, P,Brown, JAL,Joyce, MR,Kerin, MJ,Dwyer, RM (2016) 'Screening of exosomal microRNAs from colorectal cancer cells'. Cancer Biomarkers, 17 :427-435 [DOI] [Details]
(2014) 'An Alternative Estimation Approach for the Heterogeneity Linear Mixed Model'
Martinez, MJ,Holian, E (2014) 'An Alternative Estimation Approach for the Heterogeneity Linear Mixed Model'. Communications In Statistics-Simulation And Computation, 43 :2628-2638 [DOI] [Details]
(2014) 'Clustering longitudinal profiles using P-splines and mixed effects models applied to time-course gene expression data'
Coffey, N,Hinde, J,Holian, E (2014) 'Clustering longitudinal profiles using P-splines and mixed effects models applied to time-course gene expression data'. Computational Statistics & Data Analysis, 71 :14-29 [DOI] [Details]

Conference Publications

  Year Publication
(2007) 15th European Young Statisticians Meeting, EYSM 2007, Spain
Holian E. (2007) Mixture-Regression Cluster Model applied to Longitudinal Microarray Experiments 15th European Young Statisticians Meeting, EYSM 2007, Spain Spain, , 10-SEP-07 - 14-SEP-07 , pp.62-62 [Details]
(2004) 19th International Workshop on Statistical Modelling
Holian, E and Hinde, J.P (2004) Microarray experiments for gene expression studies in fish stress studies 19th International Workshop on Statistical Modelling [Details]

Abstract

  Year Publication
(2015) Exosome-mediated trafficking of microRNAs by breast cancer cells.
Joyce, DP,Glynn, CL,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, RM (2015) Exosome-mediated trafficking of microRNAs by breast cancer cells. Abstract [Details]
(2015) Investigation of exosome-encapsulated microRNAs as potential circulating biomarkers of breast cancer.
Joyce, DP,Higgins, M,Glynn, CL,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, RM (2015) Investigation of exosome-encapsulated microRNAs as potential circulating biomarkers of breast cancer. Abstract [Details]
(2015) Exosome-mediated trafficking of microRNAs by basal breast cancer cells in vitro.
Joyce, DP,Glynn, CL,Higgins, M,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, RM (2015) Exosome-mediated trafficking of microRNAs by basal breast cancer cells in vitro. Abstract [Details]
(2014) Exosome-Encapsulated MicroRNAs Secreted by Colorectal Cancer Cells: Mediators of Intercellular Cross-Talk in the Tumour Micro-Environment.
Clancy, C,Brown, J,Holian, E,Joyce, M,Kerin, MJ,Dwyer, RM (2014) Exosome-Encapsulated MicroRNAs Secreted by Colorectal Cancer Cells: Mediators of Intercellular Cross-Talk in the Tumour Micro-Environment. Abstract [Details]
(2014) Secretion of Exosome-Encapsulated MicroRNAs by Basal Breast Cancer Cells in Vitro.
Joyce, D,Glynn, C,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, R (2014) Secretion of Exosome-Encapsulated MicroRNAs by Basal Breast Cancer Cells in Vitro. Abstract [Details]

Honours and Awards

  Year Title Awarding Body
2011 Nomination for NUIG CELT teaching award -
2007 Recipient of one of two nominations awarded by the Irish Statistical Association (ISA) to represent Ireland at the European Young Statisticians Meeting EYSM 2007 Spain -
2005 Finalist - Embark Initiative Physical Sciences Communication awards Embark Initiative
2002 IRCSET scholarship IRCSET

Professional Associations

  Association Function From / To
Irish Statistical Association ISA Executive Committee member 14-MAY-08 / 11-MAY-11
Irish Statistical Association, ISA Ordinary member 12-MAY-03 /

Committees

  Committee Function From / To
School Teaching Committee Member /
Programme Board B.Sc. Mathematical Science Chair Programme Director 01-MAY-09 /
ACREC Consultant Statistician 01-JAN-14 /

Teaching Interests

Probability
Applied Statistics
Statistics for Business
Advanced Statistical Methods for Business
Statistics via Blended Learning/Distance Learning

Applications in R programming, MINITAB, SPSS

Modules Taught

  Term/Year Module Title Module Code Subject / Desc
Semester 1 2015 Inferential Statistical Methods for Business ST2217
Semester 2 2015-2016 Statistics ST113
Semester 2 2016 Advanced Statistical Methods for Business ST2218
Semester 2 2016 Introduction to Statistical Methods ST1109
Semester 1 2006 Statistics I ST237(MA237)
Semester 1 2008 Applied Statistics MA322
Semester 1 2010 Probability ST112(MA112)
Semester 1 2012-2015 Statistical Methods for Business MA109
Semester 1 2013 -2015 Applied Statistics 1 ST311
Semester 2 2008-2014 Statistical Methods for Business MA217
Semester 2 2009-2011 Mathematics & Statistics for Business MA114
Semester 2, 2009-2015 Advanced Statistical Methods in Business MA218
Year long, 2008-2014, running every 2nd year Statistics via blended learning/distance learning MA351.3

Internal Collaborators

  Name Description of Collaboration
Internal Collaborators
Affiliations: Staff member Biostatistics Unit. HRB Clinical Research Facility, Galway, (CRFG).Dr John Newell, Biostatistics Unit. HRB Clinical Research Facility, Galway, (CRFG).Prof John Hinde, Chair Statistics, School of Mathematics, Statistics and Applied Mathematics Collaborative work: Statistical Consultation,  Dr. Roisin Dwyer, REMEDI, NUIG, microarray analysis in Mesenchymal Stem Cells and Breast Cancer.   

External Collaborators

  Name Organisation / Institute Country Description of Collaboration
External Collaborators
Dr. Norma Bargary, Department of Mathematics, University of Limerick