Dr. Thomas Barry


Contact Details

Lecturer Bar/College Lecturer
Dept. of Microbiology
Arts/Science Building
NUI Galway

T: Ext. 3189
E: thomas.barry@nuigalway.ie

Microbiology
Microbiology
School of Natural Science
NUI Galway

T: +353 91 493189
E: Thomas.barry@nuigalway.ie

------------------------

 
researcher

Biography

Overview
Dr Barry is the research director of the Nucleic Acid Diagnostics Research Laboratory (NADRL) in Microbiology at NUI Galway. Research interests are focused on initial concept, biodiscovery, design, development, optimisation, validation of culture independent nucleic acid diagnostics (NAD) technologies for the detection and identification of microbial pathogens and contaminants associated with the clinical, environmental, food and pharmaceutical sectors. Dr Barry has over 20 years research experience working with industry where innovation, translation and commercialisation of NADRL NAD technologies has been achieved. These NAD infectious disease technology developments and advances have generated  funding and revenue for the NADRL through industry driven commercial product research and development, technology transfer and intellectual property licensing agreements. With NADRL technologies currently  embedded in multinational and SME companies this has resulted in diagnostics products in the marketplace or products due to be released shortly into the marketplace. 

Research Interests

MICROBIAL NUCLEIC ACID DIAGNOSTICS DEVELOPMENT
In recent years significant technical advances and developments have been made in rapid culture independent Nucleic Acid Diagnostics (NAD) technologies (in vitro amplification and sequencing) for the simultaneous detection and identification of specific microorganisms.
This has been due to the development of
- Culture independent approaches
- in vitro amplification technologies
- High throughput sample capability
- Shorter turnaround time to result
- Qualitative and quantitative capacities
- Nanotechnologies
-  Microfludics
- Automation
- High assay and sequencing specificity
- Low limits of detection
- Enhanced multiplexing
- Software developments
- User friendly interface
- Sample In result Out
Resulting in NAD technologies now being routinely used and accepted in the clinical, environmental, pharmaceutical and food industry sectors.
Currently the NADRL has NAD research projects focusing on:
Human Infectious Disease Diagnostics Assays:
- Respiratory Tract Infections and associated antimicrobial resistance.
- Fungal Diagnostics
- Small RNAs of Fungi (Cryptococcus neoformans / Pneumocystis jirovecii)
- Tuberculosis Diagnostics
- Sepsis (H. influenzae, S. pneumoniae, N. meningitidis)

Human Health Related Environmental Diagnostics Assays:
- Legionella pneumophila, Pseudomonas aeruginosa, Non tuberculosis Mycobacteria
- Legionella species genome sequencing analysis
- Nanopore sequencing of microbial communities from building water distribution systems

NADRL RESEARCH INNOVATION
Dr Barry is the lead inventor of the following granted patent microbial platform nucleic acid diagnostics infectious disease technologies:  
 
Spacer Probe Technology
(ITS - Bacterial / Fungal) Patent Number: IE128789.

RiboSEQ
(tmRNA/ ssrA - Bacterial) Patent Number: PCT/IE/00/00066 

MtSEQ
(Multiple targets - Tuberculosis) Patent Number:  PCT/IB2011/001719


NADRL RESEARCH TRANSLATION AND COMMERCIALISATION

These technologies have been licensed to 4 global multinational IVD companies. Collaborative R+D programmes have also been carried out with these licensees contributing toward technology transfer of NADRL technologies and allowing for translation of technologies. SME’s (1 Irish) with business in infectious disease diagnostics assays and diagnostics instrumentation systems have also licensed some of these technologies.

 










Research Projects

  Project Start Date End Date
RAP-ID 01-DEC-15 30-JUN-17
Towards the development of nucleic acid diagnostics assays for the quantitative detection of Pneumocystis jirovecil inpatient cohorts which will distinguish between colonisation and infection 01-OCT-15 30-SEP-19
DEVELOPMENT OF A MICROBIAL MULTIPARAMETIC NUCLEIC ACID DIAGNOSTICS TECHNOLOGY WITH POTENTIAL APPLICATION IN THE CLINICAL, FOOD AND PHARMA INDUSTRY SECTORS T BARRY 01-JAN-14 31-DEC-15
EI PC 2006 193 MYCOSEQ TOM BARRY 01-OCT-06 31-JAN-08
CCAN 2011-04B GENESCOPE (ENTERPRISE IRELAND) THOMAS BARRY 01-SEP-11 31-OCT-14
CCAN GENESCOPE AN INTEGRATED GENETIC ANALYSIS SYSTEM FOR POINT OF CARE EI THOMAS BARRY CC-2009-0002_TYNDALL 01-SEP-10 30-JUN-14
RAPID IDENTIFICATION OF RESPIRATORY TRACT INFECTIONS RID RTI EU COLLOBORATIVE THOMAS BARRY 01-JUL-12 31-DEC-16
RID-RTI 01-JUL-12 30-JUN-15
EI IF 2001 314 RIF T MRNA DR T BARRY 01-JAN-02 02-JUL-08
MULTIPAL SCLEROSIS THOMAS BARRY 31-AUG-07 31-AUG-08
EI IP 2009 0027 THOMAS BARRY 01-NOV-09 13-APR-14
DAF FIRM 04 R&D TN 271 T BARRY 01-APR-05 31-MAR-08
OVHD FROM ROG190 TOM BARRY 01-SEP-03 31-DEC-16
ENTERPRISE IRELAND DEVELOPMENT AND VALIDATION OF MOLECULAR ASSAYS CF 2011 1616 THOMAS BARRY 01-JAN-12 31-DEC-12
EI IP 2009 0027 SEROSEP THOMAS BARRY 01-NOV-09 21-JUN-12
EI CC 2008 05 10C THOMAS BARRY AN INTEGRATED GENETIC ANALYSIS SYSTEM 01-JUN-09 31-AUG-10
978 HEA BIOMED CENTRE P12 SMITH 01-OCT-99 30-MAR-09
NUC ACID PROBES MYCOPLASMA IN MS ED HOGAN 01-AUG-05 31-JUL-07
EI ATRP 2002 BRI 112 TOM BARRY NDC 01-NOV-02 31-DEC-05
FIRM AUTO TESTS FOOD PATHOGENS RD TN 116 BARRY 01-OCT-01 26-NOV-07

Peer Reviewed Journals

  Year Publication
(2015) 'Development of a rapid recombinase polymerase amplification assay for the detection of Streptococcus pneumoniae in whole blood'
Clancy, E,Higgins, O,Forrest, MS,Boo, TW,Cormican, M,Barry, T,Piepenburg, O,Smith, TJ (2015) 'Development of a rapid recombinase polymerase amplification assay for the detection of Streptococcus pneumoniae in whole blood'. BMC Infectious Diseases, 15 [DOI] [Details]
(2015) 'Solvent-selective routing for centrifugally automated solid-phase purification of RNA'
Dimov, N,Clancy, E,Gaughran, J,Boyle, D,Mc Auley, D,Glynn, MT,Dwyer, RM,Coughlan, H,Barry, T,Barrett, LM,Smith, TJ,Ducree, J (2015) 'Solvent-selective routing for centrifugally automated solid-phase purification of RNA'. Microfluidics And Nanofluidics, 18 :859-871 [DOI] [Details]
(2015) 'Comparative genome analysis identifies novel nucleic acid diagnostic targets for use in the specific detection of Haemophilus influenzae'
Helena Coughlan, Kate Reddington, Nina Tuite, Teck Wee Boo, Martin Cormican, Louise Barrett, Terry J Smith, Eoin Clancy, Thomas Barry (2015) 'Comparative genome analysis identifies novel nucleic acid diagnostic targets for use in the specific detection of Haemophilus influenzae'. Diagnostic Microbiology And Infectious Disease, 83 (2):112-116 [Details]
(2015) 'Cross Platform Standardisation of an Experimental Pipeline for Use in the Identification of Dysregulated Human Circulating MiRNAs'
Helena Kelly, Tim Downing, Nina L Tuite, Terry J Smith, Michael J Kerin, Róisín M Dwyer, Eoin Clancy, Thomas Barry, Kate Reddington (2015) 'Cross Platform Standardisation of an Experimental Pipeline for Use in the Identification of Dysregulated Human Circulating MiRNAs'. Plos One, 10 (9) [ARAN Link] [Details]
(2015) 'A rapid culture independent methodology to quantitatively detect and identify common human bacterial pathogens associated with contaminated high purity water'
Minogue E., Tuite N.L., Smith C.J., Reddington K., Barry T. (2015) 'A rapid culture independent methodology to quantitatively detect and identify common human bacterial pathogens associated with contaminated high purity water'. BMC Biotechnol, 16 (6) [DOI] [ARAN Link] [Details]
(2015) 'A comparison of established diagnostic methodologies and a novel bacterial smpB real-time PCR assay for the specific detection of Haemophilus influenzae associated with respiratory tract infections'
Kate Reddington, Stefan Schwenk, Nina Tuite, Gareth Platt, Danesh Davar, Helena Coughlan, Yoann Personne, Vanya Gant, Virve I. Enne, Alimuddin Zumla, and Thomas Barry (2015) 'A comparison of established diagnostic methodologies and a novel bacterial smpB real-time PCR assay for the specific detection of Haemophilus influenzae associated with respiratory tract infections'. Journal Of Clinical Microbiology, [DOI] [ARAN Link] [Details]
(2014) 'Rapid nucleic acid diagnostics for the detection of antimicrobial resistance in Gram-negative bacteria: is it time for a paradigm shift?'
Tuite, N,Reddington, K,Barry, T,Zumla, A,Enne, V (2014) 'Rapid nucleic acid diagnostics for the detection of antimicrobial resistance in Gram-negative bacteria: is it time for a paradigm shift?'. Journal Of Antimicrobial Chemotherapy, 69 :1729-1733 [DOI] [Details]
(2014) 'A current overview of commercially available nucleic acid diagnostics approaches to detect and identify human gastroenteritis pathogens'
Kate Reddington, Nina Tuite, Elizabeth Minogue, Thomas Barry (2014) 'A current overview of commercially available nucleic acid diagnostics approaches to detect and identify human gastroenteritis pathogens'. Biomolecular Detection and Quantification, 1 (1):3-7 [DOI] [Details]
(2013) 'Circulating miRNA biochip for diagnostic application'
M Burke, C Brougham, E Clancy, H Kelly, B Glynn, T Barry, T Smith, M Kerin (2013) 'Circulating miRNA biochip for diagnostic application'. Irish Journal Of Medical Science, 182 :127-127 [Details]
(2013) 'Diagnostics method for the rapid quantitative detection and identification of low-level contamination of high-purity water with pathogenic bacteria'
Minogue, E,Reddington, K,Dorai-Raj, S,Tuite, N,Clancy, E,Barry, T (2013) 'Diagnostics method for the rapid quantitative detection and identification of low-level contamination of high-purity water with pathogenic bacteria'. Journal Of Industrial Microbiology & Biotechnology, 40 :1005-1013 [DOI] [Details]
(2013) 'Evaluation of a novel Listeria enrichment broth combined with a real-time PCR diagnostics assay for the specific detection of Listeria monocytogenes in RTE pork products'
Gomez, D,McGuinness, S,Reddington, K,O'Grady, J,Yanguela, J,Barry, T (2013) 'Evaluation of a novel Listeria enrichment broth combined with a real-time PCR diagnostics assay for the specific detection of Listeria monocytogenes in RTE pork products'. International Journal Of Food Science And Technology, 48 :1103-1108 [DOI] [Details]
(2013) 'Advances in multiparametric molecular diagnostics technologies for respiratory tract infections'
Kate Reddington, Nina Tuite, Thomas Barry, Justin O’Grady, Alimuddin Zumla (2013) 'Advances in multiparametric molecular diagnostics technologies for respiratory tract infections'. Current opinion in pulmonary medicine, 19 (3):298-304 [Details]
(2012) 'Setting epidemiological cut-off values for Aeromonas salmonicida disc diffusion data capable of discriminating between strains on the basis of their possession of sul1 genes'
Minogue, E,Barry, T,Carroll, C,Smith, P (2012) 'Setting epidemiological cut-off values for Aeromonas salmonicida disc diffusion data capable of discriminating between strains on the basis of their possession of sul1 genes'. Aquaculture, 364 :329-332 [DOI] [Details]
(2012) 'SeekTB- A two stage multiplex real-time PCR based method for the differentiation of the Mycobacterium tuberculosis complex'
Kate Reddington, Alimuddin Zuml, Matthew Bates, Dick van Soolingen, Stefan Niemann, Thomas Barry and Justin O’Grady (2012) 'SeekTB- A two stage multiplex real-time PCR based method for the differentiation of the Mycobacterium tuberculosis complex'. Journal Of Clinical Microbiology, 50 (7):2203-2206 [DOI] [Details]
(2012) ''Development and preliminary validation of a real-time RT-PCR based method targeting tmRNA for the rapid and specific detection of Salmonella''
McGuinness S, Barry T & O'Grady J (2012) ''Development and preliminary validation of a real-time RT-PCR based method targeting tmRNA for the rapid and specific detection of Salmonella''. Food Research International, 45 :989-992 [Details]
(2012) 'Ultrathin and smooth poly(methyl methacrylate) (PMMA) films for label-free biomolecule detection with total internal reflection ellipsometry (TIRE)'
Nam, CHL,Gubala, V,Clancy, E,Barry, T,Smith, TJ,Williams, DE (2012) 'Ultrathin and smooth poly(methyl methacrylate) (PMMA) films for label-free biomolecule detection with total internal reflection ellipsometry (TIRE)'. Biosensors & Bioelectronics, 36 :250-256 [DOI] [Details]
(2012) ''Culture confirmation of Listeria monocytogenes using tmRNA as a diagnostics target''
Clancy, E., Glynn, B., Reddinton, K., Smith, T. and Barry, T. (2012) ''Culture confirmation of Listeria monocytogenes using tmRNA as a diagnostics target''. Journal Of Microbiological Methods, 88 :427-429 [Details]
(2012) ''Label-free, multiplexed detection of bacterial tmRNA using silicon photonic microring resonators''
Ott Schelera, Jared T. Kindt, Abraham J. Qavi, Lauris Kaplinski, Barry Glynn, Thomas Barry, Ants Kurg & Ryan C Bailey (2012) ''Label-free, multiplexed detection of bacterial tmRNA using silicon photonic microring resonators''. Biosensors & Bioelectronics, 36 (1):56-61 [Details]
(2011) 'High Sensitivity DNA Detection Using Gold Nanoparticle Functionalized Polyaniline Nanofibres'
Spain, E., Kojima, R., Kaner, R.B., Wallace, G.G., O’Grady, J., Lacey, K., Barry, T., Keyes, T.E. and Forster, R.J. (2011) 'High Sensitivity DNA Detection Using Gold Nanoparticle Functionalized Polyaniline Nanofibres'. Biosensors & Bioelectronics, [Details]
(2011) 'Development and evaluation of DNA and RNA real-time assays for food analysis using the hilA gene of Salmonella enterica subspecies enterica'
McCabe, EM,Burgess, CM,O'Regan, E,McGuinness, S,Barry, T,Fanning, S,Duffy, G (2011) 'Development and evaluation of DNA and RNA real-time assays for food analysis using the hilA gene of Salmonella enterica subspecies enterica'. Food Microbiology, 28 :447-456 [DOI] [Details]
(2011) 'Novel Multiplex Real-Time PCR Diagnostic Assay for Identification and Differentiation of Mycobacterium tuberculosis, Mycobacterium canettii, and Mycobacterium tuberculosis Complex Strains'
Reddington, K,O'Grady, J,Dorai-Raj, S,Maher, M,van Soolingen, D,Barry, T (2011) 'Novel Multiplex Real-Time PCR Diagnostic Assay for Identification and Differentiation of Mycobacterium tuberculosis, Mycobacterium canettii, and Mycobacterium tuberculosis Complex Strains'. Journal Of Clinical Microbiology, 49 :651-657 [DOI] [ARAN Link] [Details]
(2011) 'Detection of NASBA amplified bacterial tmRNA molecules on SLICSel designed microarray probes'
Scheler, O,Kaplinski, L,Glynn, B,Palta, P,Parkel, S,Toome, K,Maher, M,Barry, T,Remm, M,Kurg, A (2011) 'Detection of NASBA amplified bacterial tmRNA molecules on SLICSel designed microarray probes'. BMC Biotechnol, 11 (1):1-17 [DOI] [Details]
(2011) 'A Novel Multiplex Real-Time PCR for the Identification of Mycobacteria Associated with Zoonotic Tuberculosis'
Reddington, K,O'Grady, J,Dorai-Raj, S,Niemann, S,van Soolingen, D,Barry, T (2011) 'A Novel Multiplex Real-Time PCR for the Identification of Mycobacteria Associated with Zoonotic Tuberculosis'. Plos One, 6 [DOI] [Details]
(2011) ''Validation of DNA and RNA real-time assays for food analysis using the hilA gene of Salmonella enterica serovars''
McCabe, E. M., Burgess, C. M., Walsh, D., O'Regan, E., McGuinness, S., Barry, T., Fanning, S. and Duffy, G. (2011) ''Validation of DNA and RNA real-time assays for food analysis using the hilA gene of Salmonella enterica serovars''. Journal Of Microbiological Methods, [Details]
(2009) 'Rapid detection of Listeria monocytogenes in food using culture enrichment combined with real-time PCR'
O'Grady, J,Ruttledge, M,Sedano-Balbas, S,Smith, TJ,Barry, T,Maher, M (2009) 'Rapid detection of Listeria monocytogenes in food using culture enrichment combined with real-time PCR'. Food Microbiology, 26 :4-7 [DOI] [Details]
(2009) 'A novel quantitative reverse-transcription PCR (qRT-PCR) for the enumeration of total bacteria, using meat micro-flora as a model'
Dolan, A,Burgess, CM,Barry, TB,Fanning, S,Duffy, G (2009) 'A novel quantitative reverse-transcription PCR (qRT-PCR) for the enumeration of total bacteria, using meat micro-flora as a model'. Journal Of Microbiological Methods, 77 :1-7 [DOI] [Details]
(2009) 'Evaluation of a novel real-time PCR test based on the ssrA gene for the identification of group B streptococci in vaginal swabs'
Wernecke, M,Mullen, C,Sharma, V,Morrison, J,Barry, T,Maher, M,Smith, T (2009) 'Evaluation of a novel real-time PCR test based on the ssrA gene for the identification of group B streptococci in vaginal swabs'. BMC Infectious Diseases, 9 [DOI] [ARAN Link] [Details]
(2009) 'tmRNA - a novel high-copy-number RNA diagnostic target - its application for Staphylococcus aureus detection using real-time NASBA'
O'Grady, J,Lacey, K,Glynn, B,Smith, TJ,Barry, T,Maher, M (2009) 'tmRNA - a novel high-copy-number RNA diagnostic target - its application for Staphylococcus aureus detection using real-time NASBA'. Fems Microbiology Letters, 301 :218-223 [DOI] [Details]
(2009) ''Development and validation of a rapid real-time PCR based method for the specific detection of Salmonella on fresh meat''
McGuinness, S., McCabe, E., 0' Regan, E., Dolan, A., Duffy, G., Burgess, C., Fanning, S., Barry, T. and O'Grady, J. (2009) ''Development and validation of a rapid real-time PCR based method for the specific detection of Salmonella on fresh meat''. Meat Science, 83 :555-562 [Details]
(2008) 'Rapid real-time PCR detection of Listeria monocytogenes in enriched food samples based on the ssr A gene, a novel diagnostic target'
O' Grady, J., Maher, M., Smith, T and Barry T. (2008) 'Rapid real-time PCR detection of Listeria monocytogenes in enriched food samples based on the ssr A gene, a novel diagnostic target'. International Journal Of Food Microbiology, 25 :75-84 [DOI] [Details]
(2008) 'Reusable surface plasmon resonance assay for the specific detection of Streptococcus pneumoniae tmRNA'
Glynn, B,Lacey, K,O'Grady, J,Barry, T,Smith, TJ,Maher, M (2008) 'Reusable surface plasmon resonance assay for the specific detection of Streptococcus pneumoniae tmRNA'. Journal Of Rapid Methods And Automation In Microbiology, 16 :210-221 [Details]
(2008) 'Development of a real-time multiplex PCR assay for the detection of multiple Salmonella serotypes in chicken samples'
O'Regan, E,McCabe, E,Burgess, C,McGuinness, S,Barry, T,Duffy, G,Whyte, P,Fanning, S (2008) 'Development of a real-time multiplex PCR assay for the detection of multiple Salmonella serotypes in chicken samples'. BMC Microbiology, 8 [DOI] [Details]
(2007) 'Development and validation of a real-time PCR assay for the detection of group B Streptococcus in pregnant women'
Wernecke, M; Mullen, C; Maher, M; Barry, T and Smith, T. (2007) 'Development and validation of a real-time PCR assay for the detection of group B Streptococcus in pregnant women'. International Journal Of Antimicrobial Agents, 29 (2):396-396 [DOI] [Details]
(2007) ''Absence of Mycoplasma-specific DNA sequence in brain, blood and CSF of patients with multiple sclerosis (MS): A study by PCR and Real-time PCR''
Casserly, G., Barry, T., Tourtellotte W.W., Hogan, E.L. (2007) ''Absence of Mycoplasma-specific DNA sequence in brain, blood and CSF of patients with multiple sclerosis (MS): A study by PCR and Real-time PCR''. J. Neurol. Sci, 15 ((253(1-2))):48-52 [Details]
(2007) 'Quantification of Bacterial tmRNA using in vitro Transcribed RNA Standards and Two-Step qRT-PCR'
Barry Glynn, Katrina Lacey, Joanna Reilly, Terry J Smith, Thomas Barry, and Majella Maher (2007) 'Quantification of Bacterial tmRNA using in vitro Transcribed RNA Standards and Two-Step qRT-PCR'. Research Journal Of Biological Sciences, 2 (5):564-570 [Details]
(2007) 'Demonstration of the application of the tmRNA transcript of the bacterial ssrA gene as a molecular diagnostic target using a combination of NASBA and BiaCore technologies'
Glynn, B; Lacey, K; Palta, P; Kaplinski, L; Remm, M; Barry, T; Smith, T and Maher, M. (2007) 'Demonstration of the application of the tmRNA transcript of the bacterial ssrA gene as a molecular diagnostic target using a combination of NASBA and BiaCore technologies'. International Journal Of Antimicrobial Agents, 29 (2):392-392 [DOI] [Details]
(2006) 'Current and emerging molecular diagnostic technologies applicable to bacterial food safety'
BARRY GLYNN, SINEAD LAHIFF, MARTINA WERNECKE, THOMAS BARRY, TERRY J SMITH and MAJELLA MAHER (2006) 'Current and emerging molecular diagnostic technologies applicable to bacterial food safety'. Int. J. Dairy Tech, 59 (2):126-139 [Details]
(2006) 'The acetyl-cerebrosides of myelin: further characterization of novel immunogenic neural glycolipids and studies in multiple sclerosis (MS)'
EL Hogan, S Dasgupta, MA Podbielska, J O'Keefe, AP Moran, C Gately, T Barry, GM Casserly, S Levery (2006) 'The acetyl-cerebrosides of myelin: further characterization of novel immunogenic neural glycolipids and studies in multiple sclerosis (MS)'. Journal Of Neurochemistry, [Details]
(2000) 'Detection of Extended Spectrum beta-lactamase producing bacteria in Irish Hospitals and Evidence of Interhospital Spread'
Morris, D., Glennon, M., Maher, M., Barry, T., NiRiain, U., Corbett-Feeney, G.and Cormican, M. (2000) 'Detection of Extended Spectrum beta-lactamase producing bacteria in Irish Hospitals and Evidence of Interhospital Spread'. Irish Journal Of Medical Science, 169 [Details]
(1999) 'Beta-lactamases in Ireland'
Morris, D., Cormican, M., Barry, T., Corbett-Feeney, G., Flynn, J. (1999) 'Beta-lactamases in Ireland'. Irish Journal Of Medical Science, 34 [Details]
(1999) 'Molecular cloning and phylogenetic analysis of the small cytoplasmic RNA from Listeria monocytogenes'
Barry, T,Kelly, M,Glynn, B,Peden, J (1999) 'Molecular cloning and phylogenetic analysis of the small cytoplasmic RNA from Listeria monocytogenes'. Fems Microbiology Letters, 173 :47-53 [Details]
(1994) ''Clinical usefulness of detecting growth of Mycobacterium tuberculosis in positive Bactec phials using PCR'
Cormican MG, Barry T, Gannon F, Flynn J (1994) ''Clinical usefulness of detecting growth of Mycobacterium tuberculosis in positive Bactec phials using PCR'. Journal Of Clinical Pathology, 47 :190-191 [Details]
(1994) 'THE RIBOSOMAL INTERGENIC SPACER REGION - A TARGET FOR THE PCR BASED DIAGNOSIS OF TUBERCULOSIS'
GLENNON, M,SMITH, T,CORMICAN, M,NOONE, D,BARRY, T,MAHER, M,DAWSON, M,GILMARTIN, JJ,GANNON, F (1994) 'THE RIBOSOMAL INTERGENIC SPACER REGION - A TARGET FOR THE PCR BASED DIAGNOSIS OF TUBERCULOSIS'. Tubercle And Lung Disease, 75 :353-360 [Details]
(1993) 'Detection of Mycobacterium bovis in bovine blood by combined PCR and DNA probe methods'
Barry, T., Glennon, M., Smith, T.J. and Gannon, F. (1993) 'Detection of Mycobacterium bovis in bovine blood by combined PCR and DNA probe methods'. VETERINARY RECORD, 132 :66-67 [Details]
(1992) 'RAPID MINI-PREPARATIONS OF TOTAL RNA FROM BACTERIA'
Barry, T., Geary, S., Hannify, S., MacGearailt, Shalloo, M., Heery, D., Gannon, F. and Powell, P. (1992) 'RAPID MINI-PREPARATIONS OF TOTAL RNA FROM BACTERIA'. Nucleic Acid Research, [Details]
(1992) 'USE OF POLYMERASE CHAIN-REACTION FOR EARLY IDENTIFICATION OF MYCOBACTERIUM-TUBERCULOSIS IN POSITIVE CULTURES'
CORMICAN, MG,BARRY, T,GANNON, F,FLYNN, J (1992) 'USE OF POLYMERASE CHAIN-REACTION FOR EARLY IDENTIFICATION OF MYCOBACTERIUM-TUBERCULOSIS IN POSITIVE CULTURES'. Journal Of Clinical Pathology, 45 :601-604 [Details]
(1991) 'The 16s/23s ribosomal spacer region as a target for DNA probes to identify eubacteria'
Barry, T., Colleran, G. C., Glennon, M., Dunican, L. K. D. and Gannon, F. (1991) 'The 16s/23s ribosomal spacer region as a target for DNA probes to identify eubacteria'. Genome Research, [Details]
(1991) 'RAPID IDENTIFICATION OF CULTURED MYCOBACTERIUM-TUBERCULOSIS BY SPECIFIC PRIMER DIRECTED DNA AMPLIFICATION'
Cormican, M. G., Barry, T., Gannon, F. and Flynn, J. (1991) 'RAPID IDENTIFICATION OF CULTURED MYCOBACTERIUM-TUBERCULOSIS BY SPECIFIC PRIMER DIRECTED DNA AMPLIFICATION'. Journal Of Medical Microbiology, [Details]
(1991) 'Direct genomic DNA amplification from autoclaved infectious microorganisms using PCR technology'
Barry, T. and Gannon, F. (1991) 'Direct genomic DNA amplification from autoclaved infectious microorganisms using PCR technology'. Genome Research, (1):75-75 [Details]
(1990) 'A rapid procedure to isolate major abundance mRNA transcripts and study the transcription profile of a tissue'
Powell, R, Byrnes L, Barry T and Gannon, F (1990) 'A rapid procedure to isolate major abundance mRNA transcripts and study the transcription profile of a tissue'. Technique, 2 :213-215 [Details]
(1990) 'Transgenic farm animals'
Gannon, F.;Powell, R.; Barry, T.; McEvoy, T.G.; Sreenan, J.M. (1990) 'Transgenic farm animals'. Journal Of Biotechnology, [Details]
(1990) 'The polymerase chain reaction'
Barry, T. and Gannon, F. (1990) 'The polymerase chain reaction'. British Journal Of Biomedical Science, 1 :8-17 [Details]
(1990) 'A GENERAL-METHOD TO GENERATE DNA PROBES FOR MICROORGANISMS'
BARRY, T,POWELL, R,GANNON, F (1990) 'A GENERAL-METHOD TO GENERATE DNA PROBES FOR MICROORGANISMS'. Nature Biotechnology, 8 :233-236 [Details]
(1989) 'THE IDENTIFICATION OF CDNA CLONES THAT INCLUDE THE 3' END OF MESSENGER-RNA'
BARRY, T,STACK, M,MORGAN, A,GANNON, F (1989) 'THE IDENTIFICATION OF CDNA CLONES THAT INCLUDE THE 3' END OF MESSENGER-RNA'. Gene Analysis Techniques, 6 :21-23 [Details]
(1988) 'THE EXPRESSION OF A FOREIGN GENE IN SALMON EMBRYOS'
MCEVOY, T,STACK, M,KEANE, B,BARRY, T,SREENAN, J,GANNON, F (1988) 'THE EXPRESSION OF A FOREIGN GENE IN SALMON EMBRYOS'. Aquaculture, 68 :27-37 [Details]
(1987) 'DIRECT GENE-TRANSFER BY MICROINJECTION'
MCEVOY, TG,STACK, M,BARRY, T,KEANE, B,GANNON, F,SREENAN, JM (1987) 'DIRECT GENE-TRANSFER BY MICROINJECTION'. Theriogenology, 27 :258-258 [Details]
(1984) 'TOWARDS THE CLONING OF THE CALF PROCHYMOSIN GENE'
MCCONNELL, DJ,HUGHES, D,CHEN, YF,CARROLL, DP,DONNELLY, WJ,OLLINGTON, JF,QUINN, D,BARRY, T,GANNON, F (1984) 'TOWARDS THE CLONING OF THE CALF PROCHYMOSIN GENE'. Biochemical Society Transactions, :487-488 [Details]

Book Chapters

  Year Publication
(2014) 'Future of Molecular Diagnostics: The Example of Infectious Diseases'
Eoin Clancy, Kate Reddington, Thomas Barry, Jim Huggett and Justin O'Grady (2014) 'Future of Molecular Diagnostics: The Example of Infectious Diseases' In: Molecular Diagnostics: Current Research and Applications. UK: Caister Academic Press. [Details]

Conference Publications

  Year Publication
(2013) 17th International Conference on Solid-State Sensors, Actuators & Microsystems
Gaughran, J., Dimov, N., Clancy, E., Barry, T., Smith, T., Ducrée, J. (2013) Multi-stage, solvent-controlled routing for automated on-disc extraction of total RNA from breast cancer cell line homogenate 17th International Conference on Solid-State Sensors, Actuators & Microsystems Barcelona, Spain, , 16-JUN-13 - 20-JUN-13 [Details]
(2013) 17th International Conference on Solid-State Sensors, Actuators & Microsystems
Dimov, N., Gaughran, J., Clancy, E., Barry, T., Smith, T., Ducrée, J. (2013) Automated on-disc total RNA extraction from whole blood towards point-of-care for early-stage diagnostics 17th International Conference on Solid-State Sensors, Actuators & Microsystems Barcelona, , 16-JUN-13 - 20-JUN-13 [Details]
(2012) Eur. Congress of Clinical Microbiology and Infectious Diseases (ECCMID) Annual Conference
O'Connor, L., Lahiff, S., Reddington, K., Minogue, E., McShera, K., Fahy, C., Devany, S., Smith, T.J., Barry, T (2012) Development of nucleic acid-based diagnostic tests for the detection of microbial pathogens using novel targets Eur. Congress of Clinical Microbiology and Infectious Diseases (ECCMID) Annual Conference London, , 31-MAR-12 - 03-APR-12 [Details]
(2011) 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Linares, A.V., Gorkin, R., Glynn, B., Godino, N., Miller, N., Kerin, M., Barry, T., Smith, T. and Ducrée, J. (2011) Purification of miRNA from whole blood by chemical lysis and phase separation in a centrifugo-pneumatic micro-homogenizer 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences Seattle, Washington, USA, , 02-OCT-11 - 06-OCT-11 [Details]
(2010) European Conference of Clinical Microbiology and Infectious Diseases
Glynn, B., Lacey, K., Palta, P., Kaplinski, L., Remm, M., Barry, T., Smith, T. and Maher M. (2010) Demonstration of the application of the tmRNA transcript of the bacterial ssrA gene as a molecular diagnostic target using a combination of NASBA and BiaCore technologies European Conference of Clinical Microbiology and Infectious Diseases Munich, Germany, [Details]
(2010) 5th IDF Mastitis Conference, Christchurch, New Zealand
Clancy, E., Dimov, I. K., Garcia-Cordero, J. L., O'Grady, J., Barry, T., Maher, M., Smith, T., Ricco, A. J. (2010) Towards the development of integrated microfluidic sample-in-answer-out devices for the detection of mastitis causing pathogens 5th IDF Mastitis Conference, Christchurch, New Zealand , 21-MAR-10 - 24-MAR-10 [Details]
(2009) 4th International qPCR Conference Diagnostics & Molecular Markers
Grady, J., Mullen, C., Jankiewicz, M., Lacey, K., Tuite, N. L., O’ Connor, L., Maher, M., Barry, T., and Smith, T. (2009) Nucleic acid diagnostic tests for the detection of microbial pathogens 4th International qPCR Conference Diagnostics & Molecular Markers Technical University of Munich, Germany, [Details]
(2009) European Molecular Diagnostics Congress
Maher, M., O’ Connor, L., Glynn, B., Wernecke, M., Mullen, C., O’ Grady, J., Lacey, K., McGuinness, S., Clancy, E., Tuite, N., Lahiff, S., Barry, T. and Smith, T. (2009) Nucleic acid diagnostic tests for the detection of microbial pathogens European Molecular Diagnostics Congress Stockholm, Sweden, [Details]
(2009) Proc. MEMS 2009, IEEE: New York
Garcia-Cordero J.L., Dimov I.K., O'Grady J., Ducree J., Barry T., and Ricco A.J. (2009) Monolithic Centrifugal Microfluidic Platform for Bacteria Capture and Concentration, Lysis, Nucleic-Acid Amplification and Real Time Detection Proc. MEMS 2009, IEEE: New York [Details]
(2009) The 6th European Molecular Diagnostics Conference
Maher, M., O’ Connor, L., Glynn, B., Tuite, N., Mullen, C., O’ Grady, J., McGuinness, S., Nielsen, S., Smith, T. and Barry, T. (2009) Nucleic acid diagnostic tests based on novel molecular targets for the detection of microbial pathogens The 6th European Molecular Diagnostics Conference The Hague, Netherlands, [Details]
(2008) The Knowledge Foundation’s 13th International Conference. DETECTION TECHNOLOGIES 2008
Tuite, N. L., O’Grady, J., McGuinness, S., O’Connor, L., Maher, M., Smith, T. and Barry, T. (2008) Development of nucleic acid diagnostic tests for detection of microbial pathogens The Knowledge Foundation’s 13th International Conference. DETECTION TECHNOLOGIES 2008 Phoenix, Arizona, USA, [Details]
(2008) Proceedings of the IEEE SENSORS Conference, Italy. Sensor 2008 IEEE
Glynn, B., Scheler, O., Parkel, S., Kurg, A., Barry, T., Smith, T. and Maher, M. (2008) Mircoarray detection of labeled NASBA products for the specific identification of pathogenic bacteria using tmRNA as a target Proceedings of the IEEE SENSORS Conference, Italy. Sensor 2008 IEEE , pp.1072-1075 [Details]
(2007) 17th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) & 25th International Congress of Chemotherapy (ICC)
B Glynn, K Lacey, P Palta, L Kaplinski, M Remm, T Barry, T Smith, M Maher (2007) Demonstration of the application of the tmRNA transcript of the bacterial ssrA gene as a molecular diagnostic target using a combination of NASBA and BiaCore technologies 17th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) & 25th International Congress of Chemotherapy (ICC) Munich, Germany, , 31-MAR-07 - 03-APR-07 [Details]
(2006) Journal of Neurochemistry
HOGAN, E.L., DASGUPTA, S., PODBIELSKA, M.A., O'KEEFFE, J., MORAN, A.P., GATELY, C., BARRY, T., CASSERLY, G.M. & LEVERY, S. (2006) The acetyl-cerebosides of myelin: further charcaterization of novel immunogenic neural glycolipids and studies in multiple sclerosis (MS) Journal of Neurochemistry [Details]
(2006) Society of Dairy Technology Conference 2006
Glynn, B., Lahiff, S., Wernecke, M., Barry, T., Smith, T.J., Maher, M. (2006) Current and emerging molecular diagnostics technologies applicable to bacterial food control Society of Dairy Technology Conference 2006 , pp.126-139 [Details]
(2006) 52nd International Congress of Meat Science and Technology (52nd ICoMST)
A. Dolan, C. Burgess, T. Barry, S. Fanning and G. Duffy (2006) Quantification of total viable counts (TVC'S) on fresh meat carcasses by a novel real-time PCR reaction 52nd International Congress of Meat Science and Technology (52nd ICoMST) [Details]
(2006) 52nd International Congress of Meat Science and Technology (52nd ICoMST)
E. McCabe, C. Burgess, S. Fanning, T. Barry and G. Duffy (2006) Toward the developement of a rapid nucleic acid based technique for the sensitive and specific detection of Salmonella spp on fresh meat 52nd International Congress of Meat Science and Technology (52nd ICoMST) [Details]
(2000) 99th General Meeting of the American Society of Microbiology
Morris D., Glennon M, Maher M, Ni Riain U, Barry T, Corbett-Feeney G, Cormican M (2000) Evidence of interhospital spread of extended spectrum beta-lactamase producing bacteria in Ireland 99th General Meeting of the American Society of Microbiology [Details]
(1990) 5th European Congress on Biotechnology
Colleran, G. C., Barry, T., Powell, R., Dunican, L. K. and Gannon, F. (1990) Rapid analysis of an aberrant region of the ribosomal operon from a selection of Clostridial species using PCR: A New Taxonomic Approach 5th European Congress on Biotechnology Holland, , pp.410-413 [Details]
(1988) Proc. 11th Intl. Congr. Anim. Reprod
McEvoy, T.G. and Barry, T. (1988) Ovum survival in atlantic salmon following gene transfer by cytoplasmic injection Proc. 11th Intl. Congr. Anim. Reprod [Details]

Conference Contributions

  Year Publication
(2015) International Biodeterioration & Biodegradation Society and Public Health England Meeting: “Water Microbiology - Current and Emerging Issues in Healthcare,
Kate Reddington*, Elizabeth Minogue, Nina Tuite, Thomas Barry (2015) Real-time PCR diagnostics assays to quantitatively detect and identify human pathogenic microorganisms from water, water distribution and premise plumbing systems. [Oral Presentation], International Biodeterioration & Biodegradation Society and Public Health England Meeting: “Water Microbiology - Current and Emerging Issues in Healthcare, University of Winchester, UK , 08-SEP-15 - 09-SEP-15. [Details]
(2015) 3rd qPCR and Digital PCR Congress,
Thomas Barry (2015) qPCR Diagnostic Assay Development for Infectious Disease. [Invited Oral Presentation], 3rd qPCR and Digital PCR Congress, London , 20-OCT-15 - 21-OCT-15. [Details]
(2014) Microbiology & Infectious Diseases Congress Europe Conference,
Elizabeth Minogue, Kate Reddington, Katrina Lacey, Nina Tuite and Thomas Barry. (2014) Design and optimisation of a real-time PCR diagnostics assay to quantitatively detect and identify Legionella spp. [Poster Presentation], Microbiology & Infectious Diseases Congress Europe Conference, London, UK , 29-SEP-14 - 30-SEP-14. [Details]
(2015) Irish Molecular Diagnostics Network,
Thomas Barry (2015) qPCR Diagnostic Assay Development for Infectious Disease - Working with Industry - an Academics Perspective. [Invited Oral Presentation], Irish Molecular Diagnostics Network, Dublin , 09-OCT-15 - 09-OCT-15. [Details]
(2014) Microbiology and Infectious Diseases Asia Conference,
Thomas Barry (2014) Infectious Disease Nucleic Acid Diagnostics Commercialisation - An Academics Prespective. [Invited Oral Presentation], Microbiology and Infectious Diseases Asia Conference, Singapore , 10-JUN-14 - 11-JUN-14. [Details]
(2014) ECCMID,
EU FP 7 Consortuium - NUIG, ULC, Mobidiag and Gnenwave (2014) Rapid Diaganostics of Respiratory Tract Infections - Diagnostics for Infectious Diseases in Humans. [Poster Presentation (Refereed)], ECCMID, Barcelona, Spain , 10-MAY-14 - 13-MAY-14. [Details]
(2013) Rapid Methods Europe: Food Feed Water Analysis - Innovation and Breakthroughs,
Elizabeth Minogue, Kate Reddington, Nina Tuite, Eoin Clancy,Thomas Barry (2013) Diagnostics method for the rapid detection and identification of low level contamination of water systems with human pathogenic bacteria. [Poster Presentation (Refereed)], Rapid Methods Europe: Food Feed Water Analysis - Innovation and Breakthroughs, Noordwijkerhout, the Netherlands , 21-JAN-13 - 23-JAN-13. [Details]
(2013) SFI BDI-2 mid-term review,
Helena Coughlan, Eoin Clancy, Agnieszka Wróbel, Terry Smith and Thomas Barry (2013) Development of a tmRNA based NASBA Assay for the deection of Neisseria meningitidis. [Poster Presentation], SFI BDI-2 mid-term review, Biomedical Diagnostics institute, Dublin City University , 24-JUN-13 - 24-JUN-13. [Details]
(2013) College of Science and the College of Engineering & Informatics, NUIG and UL Research Day,
Elizabeth Minogue, Kate Reddington, Nina Tuite, Eoin Clancy, Thomas Barry (2013) Diagnostics method for the rapid, quantitative detection and identification of low level contamination of high purity water with pathogenic bacteria. [Poster Presentation (Refereed)], College of Science and the College of Engineering & Informatics, NUIG and UL Research Day, Bailey Allen Hall, NUIG , 11-APR-13 - 11-APR-13. [Details]
(2012) BDI technology Showcase,
Eoin Clancy, Helena Coughlan, Terry Smith and Thomas Barry (2012) Development of a tmRNA based NASBA assay for the detection of Neisseria meningitidis. [Poster Presentation], BDI technology Showcase, Biomedical Diagnostics Institute, Dublin City University, Ireland , 08-MAR-12 - 08-MAR-12. [Details]
(2012) 22nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID),
O'Connor L, Lahiff S, Reddington K, Minogue E, McShera K, Fahy C, Devany S, Smith T, Barry T. (2012) Development of nucleic acid-based diagnostic tests for the detection of microbial pathogens using novel targets. [Poster Presentation (Refereed)], 22nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), London, United Kingdom , 31-MAR-12 - 03-APR-12. [Details]
(2012) Europtorde XI,
Dirk Kurzbuch, Eoin Clancy, Thomas Barry and Colette McDonagh (2012) High efficiency ring lens based Supercritical Angle Fluorescence (SAF) detection for optimum bioassay performance. [Poster Presentation], Europtorde XI, Barcelona, Spain , 01-APR-12 - 04-APR-12. [Details]
(2012) BDI Scientific Advisory Board meeting,
M. Burke , C. Brougham, E. Clancy, H. Kelly, B. Glynn, T. Barry, T. Smith and M. Kerin (2012) Circulating miRNA Biochip for Diagnostic Application. [Poster Presentation], BDI Scientific Advisory Board meeting, DCU, Dublin, Ireland , 10-OCT-12 - 10-OCT-12. [Details]
(2012) BDI Scientific Advisory Board meeting,
Eoin Clancy, Helena Coughlan, Terry Smith and Thomas Barry (2012) Development of a tmRNA based NASBA Assay for the Detection of Neisseria meningitidis. [Poster Presentation], BDI Scientific Advisory Board meeting, DCU, Dublin, Ireland , 10-OCT-12 - 10-OCT-12. [Details]
(2012) Emerging Treatments for Lung Diseases: Progress, Challenges and Opportunities from an Irish Perspective,
L. O’Connor, S. Lahiff, K. Reddington, N. L. Tuite, T. Barry, T. J. Smith (2012) Molecular Diagnostics for Respiratory Infections. [Poster Presentation], Emerging Treatments for Lung Diseases: Progress, Challenges and Opportunities from an Irish Perspective, RIA Dublin , 07-SEP-12 - 07-SEP-12. [Details]
(2012) NanoNet Ireland, “Nanoscience Excellence with Impact”,
Des Brennan, Barry Glynn, Thomas Barry, Peter Curley,Michael O’Donovan,Conor Burke,Colette McDonagh, Gemma Keegan, Paul Galvin. (2012) GENESCOPE: AN INTEGRATED GENETIC ANALYSIS SYSTEM FOR POINT OF CARE MOLECULAR DIAGNOSTICS. [Poster Presentation], NanoNet Ireland, “Nanoscience Excellence with Impact”, Science Gallery, Trinity College Dublin , 17-SEP-12 - 18-SEP-12. [Details]
(2012) NUI Galway Genomics Workshop,
Helena Kelly and Thomas Barry (2012) Analysis of differentially expressed circulating miRNA profiles in healthy and breast cancer whole blood samples using a next generation sequencing approach. [Invited Oral Presentation], NUI Galway Genomics Workshop, School of Maths, Aras de Brun, NUIG , 25-MAY-12 - 25-MAY-12. [Details]
(2012) Colloids and Nanomedicine,
G. Keegan, B. Glynn, D. Brennan, T. Barry, P. Galvin, C. McDonagh. (2012) A plasmonic silver nanoparticle platform for sensitive DNA detection. [Poster Presentation], Colloids and Nanomedicine, Amsterdam, The Netherlands , 15-JUL-12 - 17-JUL-12. [Details]
(2012) Royal Academy of Medicine in Ireland annual meeting,
M. Burke, C. Brougham, E. Clancy, H. Kelly, B. Glynn, T. Barry, T. Smith, M. Kerin (2012) Circulating miRNA biochip for diagnostics application. [Poster Presentation], Royal Academy of Medicine in Ireland annual meeting, Galway, Ireland , 20-JUN-12 - 20-JUN-12. [Details]
(2012) CMOD 10th Annual Cardiovascular Biomarkers Symposium and Irish Biomarker Network Workshop,
Thomas Barry (2012) “Commercialising Biomarkers: Academic Perspective”. [Invited Oral Presentation], CMOD 10th Annual Cardiovascular Biomarkers Symposium and Irish Biomarker Network Workshop, Dublin , 01-MAY-12 - 02-MAY-12. [Details]
(2011) 32nd annual European Society of Mycobacteriology Conference,
Kate Reddington, Justin O’ Grady, Siobhan Dorai-Raj, Stefan Niemann, Dick van Soolingen and Thomas Barry (2011) A Novel Multiplex Real -Time PCR for the Identification of Mycobacteria Associated with Zoonotic Tuberculosis . [Invited Oral Presentation], 32nd annual European Society of Mycobacteriology Conference, Lubeck, Germany , 26-JUN-11 - 28-JUN-11. [Details]
(2011) Meningitis & Septicaemia in children and adults,
Eoin Clancy, Helena Coughlan, Terry Smith and Thomas Barry (2011) Development of a tmRNA based NASBA assay for the detection of Neisseria meningitidis. [Poster Presentation], Meningitis & Septicaemia in children and adults, London, UK , 08-NOV-11 - 09-NOV-11. [Details]
(2011) Rapid Methods Europe 2011 7th Conference Driving food and feed analysis forward!,
Thomas Barry (2011) Food pathogen diagnostics: can anything be learned from the medical molecular-based diagnostics sector?. [Plenary Lecture], Rapid Methods Europe 2011 7th Conference Driving food and feed analysis forward!, The Netherlands , 24-JAN-11 - 26-JAN-11. [Details]
(2010) SFI / MMI Conference,
Thomas Barry (2010) Technology Platforms Web-portal and Workshop. [Invited Lecture], SFI / MMI Conference, St. James Hospital Dublin , 03-JUN-10 - 03-JUN-10. [Details]
(2010) Materials Ireland,
Clancy, E., Nooney, R., Gubala, V., MacCraith, B., Glynn, B., Barry, T., Maher, M., Smith, T., (2010) Nanoparticles as detection labels for the detection of pathogenic bacteria. [Poster Presentation], Materials Ireland, Cork, Ireland , 13-DEC-10 - 13-DEC-10. [Details]
(2010) Advances in Biodetection technologies,
Thomas Barry (2010) Nucleic acid Diagnostics based on novel targets for the detection of microbial pathogens. [Invited Lecture], Advances in Biodetection technologies, Dublin , 26-MAY-10 - 26-MAY-10. [Details]
(2010) MEDTEC, Technical Innovation Forum,
Thomas Barry (2010) MDRG - Commercialisation of Diagnostics Technologies. [Invited Oral Presentation], MEDTEC, Technical Innovation Forum, Galway, Ireland , 05-OCT-10 - 06-OCT-10. [Details]
(2010) The Irish Biomarker Network - Inaugural Workshop,
Thomas Barry (2010) Molecular Diagnostics Research Group Commercialisation Activities. [Invited Lecture], The Irish Biomarker Network - Inaugural Workshop, Dublin , 04-NOV-10 - 04-NOV-10. [Details]
(2010) Society of General Microbiology,
Reddington K , McGuinness S, Nielsen S, Tuite N, O’Grady J, Mullen C, Wernecke M, Lacey K, Clancy E, Brennan C, Jankiewicz M, Lahiff S, Dorai Raj S, Glynn B, O’Connor L, Smith T, Barry T (2010) Nucleic acid diagnostic tests using novel molecular targets for the detection of microbial pathogens. [Poster Presentation], Society of General Microbiology, NUIG, Galway, Ireland , 15-APR-10 - 16-APR-10. [Details]
(2010) Science Experience Workshop,
Thomas Barry (2010) Innovation & Commercialisation in Science. [Invited Lecture], Science Experience Workshop, NUIG , 24-AUG-10 - 25-JUN-10. [Details]
(2009) International Sensors Workshop,
O' Grady, J., Lacey, K., Lahiff, S., Glynn, B., Maher, M. Barry, T. and Smith T. (2009) Sandwich ELISA based on the RiboSEQ platform for direct detection of Staphylococcus aureus. [Poster Presentation], International Sensors Workshop, DCU , 05-JUN-09 - 05-JUN-09. [Details]
(2009) NanoBioTech,
Glynn, B., Clancy, E., Maher, M., Smith, T. and Barry, T. (2009) Innovative nucleic acid targets for nanotechnology-based microorganism detection. [Poster Presentation], NanoBioTech, Montreux, Switzerland , 16-NOV-09 - 18-NOV-09. [Details]
(2009) 4th International qPCR Event 'Diagnostics & Molecular Markers',
O’ Grady, J., Mullen, C., Jankiewicz, M., Lacey, K., Tuite, N. L., O’ Connor, L., Maher, M., Barry, T., and Smith, T. (2009) Nucleic acid diagnostic tests for the detection of microbial pathogens. [Poster Presentation], 4th International qPCR Event 'Diagnostics & Molecular Markers', Technical University of Munich, Germany , 23-MAR-09 - 26-MAR-09. [Details]
(2009) MEDTEC, Technical Innovation Forum,
Thomas Barry (2009) Molecular Diagnostics Assay Development: From Discovery to Commercial Technology Development. [Invited Lecture], MEDTEC, Technical Innovation Forum, Galway , 23-SEP-09 - 23-SEP-09. [Details]
(2009) ICTBSB 2009,
Eoin Clancy, Katrina Lacey, Justin O’Grady, Dirk Kurzbuc, Lourdes Basabe Desmonts, Vladimir Gubala, Thomas Barry, Majella Maher and Terry Smith (2009) Development of a nucleic acid assay for the detection of bacteria by supercritical angle fluorescence. [Poster Presentation], ICTBSB 2009, Dublin, Ireland , 26-JAN-09 - 28-JAN-09. [Details]
(2009) Advancing Beef Safety through Research and Innovation,
E. Mc Cabe, C. Burgess, Edel O’Regan, Sheila Mc Guinness, T. Barry, S. Fanning and G. Duffy (2009) Validation of a DNA and a RNA real time assay for detection of Salmonella enterica on fresh beef carcasses. [Poster Presentation], Advancing Beef Safety through Research and Innovation, Ashtown Food Research Conference Centre, Teagasc, Dublin, Ireland , 25-MAR-09 - 26-MAR-09. [Details]
(2009) Advancing Beef Safety through Research and Innovation,
CM Burgess, A Dolan, T Barry, S Fanning and G Duffy (2009) Validation of a quantitative real time PCR assay for enumerating total viable counts on beef carcasses. [Poster Presentation], Advancing Beef Safety through Research and Innovation, Ashtown Food Research Conference Centre, Teagasc, Dublin, Ireland , 25-MAR-09 - 26-MAR-09. [Details]
(2009) Advances in Microarray Technology,
Majella Maher, Louise O’connor, Barry Glynn, Martin Wernecke, Ciara Mullen, Justin O’Grady, Katrin Lacey, Sheila McGuinness, Eoin Clancy, Nina Tuite, Sinead lahiff, Thomas Barry and Terry Smith (2009) Nucleic acid diagnostic tests for the detection of microbial pathogens. [Poster Presentation], Advances in Microarray Technology, Stockholm, Sweden , 19-MAY-09 - 20-MAY-09. [Details]
(2009) The 6th European Molecular Diagnostics Conference,,
Maher, M., O’ Connor, L., Glynn, B., Tuite, N., Mullen, C., O’ Grady, J., McGuinness, S., Nielsen, S., Smith, T. and Barry, T. (2009) Nucleic acid diagnostic tests based on novel molecular targets for the detection of microbial pathogens. [Poster Presentation], The 6th European Molecular Diagnostics Conference,, The Hague, Netherlands, October 2009 , 19-OCT-09 - 22-OCT-09. [Details]
(2009) Strategy for maximising the national contribution and commercialisation opportunities from FIRM projects,
Thomas Barry (2009) The Molecular Diagnostics Research Group. [Invited Lecture], Strategy for maximising the national contribution and commercialisation opportunities from FIRM projects, Portloaise , 30-APR-09 - 30-APR-09. [Details]
(2008) The Knowledge Foundation's 13th International Conference: Detection Technologies-New Developments in identification of microorganisms and chemicals,
Thomas Barry (2008) Molecular target discovery for application in nucleic acid based diagnostics for pathogens. [Invited Lecture], The Knowledge Foundation's 13th International Conference: Detection Technologies-New Developments in identification of microorganisms and chemicals, Phoenix, Arizona, USA , 08-OCT-08 - 09-OCT-09. [Details]
(2008) Rapid Molecular Methods for Microbial Detection in Food,
Thomas Barry (2008) Real-time in vitro amplification technologies for food related diagnostics. [Oral Presentation], Rapid Molecular Methods for Microbial Detection in Food, Ashtown Food Research Centre, Teagasc, Dublin 15 , 01-MAY-08 - 01-MAY-08. [Details]
(2008) Detection Technologies. New Developments in Identification of Microorganisms & Chemicals,
Nina L. Tuite, Justin O’Grady, Sheila McGuinness, Louise O’Connor, Majella Maher, Terry Smith, and Thomas Barry (2008) Development of nucleic acid diagnostic tests for detection of microbial pathogens. [Poster Presentation], Detection Technologies. New Developments in Identification of Microorganisms & Chemicals, Phoenix, AZ USA , 03-NOV-08 - 06-NOV-08. [Details]
(2007) FEMS International Conference on Chlamydia and Mycoplasma Human Infections,
HOGAN, E.L, BARRY, T., DASGUPTA, S., ANNUK, H., CASSERLY, G.M., PODBIELSKA, M.A., LEVERY, S. & MORAN, A.P. (2007) Possible mycoplasma infection in MS: study of immunogenic glycolipids and search for mycoplasma DNA. [Poster Presentation], FEMS International Conference on Chlamydia and Mycoplasma Human Infections, University of Ferrara, Italy , 19-APR-07 - 20-APR-07. [Details]
(2007) US-Ireland R&D partnership: Sensors workshop,
Glynn, B., O' Grady, J., Lacey, K., Maher, M., Barry, T. and Smith, T. (2007) SLIC Biosensors in Molecular Diagnostics: Nanotechnology for analysis of species-specific microbial transcripts. [Poster Presentation], US-Ireland R&D partnership: Sensors workshop, DCU , 16-AUG-07 - 17-AUG-07. [Details]
(2007) Sensors Workshop,
O' Grady, J., Lacey, K., Lahiff, S., Glynn, B., Maher, M. Barry, T. and Smith T. (2007) Sandwich ELISA based on the RiboSEQ platform for direct detection of Staphylococcus aureus. [Poster Presentation], Sensors Workshop, NUI Galway , 13-SEP-07 - 14-SEP-07. [Details]
(2007) Society of General Microbiology Meeting,
Mullen, C., Wernecke, M., Morrison, J., Sharma, V., Barry, T., Smith, T. and Maher, M. (2007) Development of a real-time PCR assay for the identification of Group B Streptococcus in pregnant women. [Poster Presentation], Society of General Microbiology Meeting, University of Limerick , 03-APR-08 - 04-APR-08. [Details]
(2002) Food Institutional Research Measure,
M. Maher, M. Cormican, C. Carroll and T. Barry (2002) Food Research Related Activities at NUIG. [Poster Presentation], Food Institutional Research Measure, University CollegeDublin , 01-AUG-02 - 02-AUG-02. [Details]
(2001) SGM Irish Branch Meeting,
Bohane, H., O'Connor, L., Barry, T., Glennon, M., Cormican, M., Smith, T. & Maher, M. (2001) tmRNA a Novel Target for Rapid Diagnosis of the Mycobacterium tuberculosis Complex. [Poster Presentation], SGM Irish Branch Meeting, Maynooth, Ireland , 23-JAN-01 - 24-JAN-00. [Details]
(2000) SGM Irish Branch Meeting,
Kelliher, F., Glynn, B., Smith, T. & Barry, T. (2000) tmRNA as an indicator of bacterial viability - A preliminary experimental analysis. [Poster Presentation], SGM Irish Branch Meeting, Maynooth, Ireland , 24-JAN-00 - 25-JAN-01. [Details]
(2000) Western Alliance at NCBES,
Phelan, D., Glynn, B., Papkovsky, D., A., A., Morgan, F., Redfern, M. & Barry, T. (2000) An integrated Research Strategy for the Development of Small to Medium Sized Nucleic Acid Microarrays for Diagnostics. [Poster Presentation], Western Alliance at NCBES, NUIG , 03-AUG-00 - 04-AUG-00. [Details]
(2000) Emerging Issues in Food Safety,
Dorai-Raj, S., O'Grady, J., Glynn, B., O'Connor, L., Maher, M., Smith, T. & Barry, T. (2000) tmRNA - A Novel Nucleic Acid Target for Eubacterial Diagnostics. [Poster Presentation], Emerging Issues in Food Safety, Cork, Ireland , 20-JUN-00 - 23-JUN-00. [Details]
(2000) Amercian Society for Microbiology,
Morris, D., Glennon, M., Barry, T., Corbett-Feeney, G. and Cormican, M. (2000) Evidence of interhospital spread of ESBL producing bacteria in Ireland. [Poster Presentation], Amercian Society for Microbiology, Los Angeles, USA , 21-MAY-00 - 25-MAY-01. [Details]
(1997) Microbial Response to Stress: What's new and how it can be applied? European Federation of Biotechnology Working Party of Microbial Physiology,
Cleary, B., Glynn, B., Dalton, S. and Barry, T. (1997) The nature and extent of 3' post-transcriptional adenylation of RNA in the life-cycle of bacteria grown in batch culture. [Poster Presentation], Microbial Response to Stress: What's new and how it can be applied? European Federation of Biotechnology Working Party of Microbial Physiology, Sesimbra, Portugal , 15-MAR-97 - 17-MAR-97. [Details]
(1997) Irish geneticists meeting,
Cleary, B., Glynn, B., Dalton, S. and Barry, T. (1997) Poly (A) polymerase mediated decay of redundant ribosomal RNA in stationary phase Escherichia coli. [Poster Presentation], Irish geneticists meeting, University College Galway, Ireland , 23-APR-97 - 25-APR-97. [Details]
(1996) Society for General Microbiology,
Cleary, B. & Barry, T. (1996) The application of differential display reverse transcriptase polymerase chain reaction (DDRT-PCR) to monitor temporo-spatial gene expression in Escherichia coli. [Poster Presentation], Society for General Microbiology, University College, Galway , 26-MAY-96 - 27-MAY-96. [Details]
(1996) Society for General Microbiology Irish Branch Symposium on Global Control of Transcription in Prokaryotes,
Cleary, B., Glynn, B. and Barry, T. (1996) 3' Post-transcriptional adenylation of Escherichia coli RNA is primarily associated with stationary phase. [Poster Presentation], Society for General Microbiology Irish Branch Symposium on Global Control of Transcription in Prokaryotes, Trinity College, Dublin , 11-JAN-96 - 12-JAN-96. [Details]
(1995) Society for General Microbiology,
Peden, J. and Barry, T (1995) Molecular characterisation and phylogenetic analysis of the small cytoplasmic RNA associated with the ribonucleoprotein signal recognition particle from Listeria monocytogenes. [Poster Presentation], Society for General Microbiology, Cork, Ireland , 28-APR-95 - 29-APR-95. [Details]
(1993) American Society for Microbiology,
Smith, T. Glennon, M., Barry, T. and Gannon, F (1993) The direct detection of Mycobacterium Bovis in blood of cattle using the polymerase chain reaction. [Poster Presentation], American Society for Microbiology, New Orleans, USA , 11-DEC-93 - 14-DEC-93. [Details]
(1993) Sixth European Congress on Biotechnology,
Colleran, G., Barry, T., Glennon, M., Gannon, F. and Dunican, L.K (1993) Direct Detection of Clostridium tyrobutyricum in Milk by a Specific Polymerase Chain Reaction Coupled Oligomer Probe Assay. [Poster Presentation], Sixth European Congress on Biotechnology, Florence, Italy , 13-JUN-93 - 17-JUN-93. [Details]
(1989) 4th European Association of Fish Pathologists. Diseases of Fish and Shellfish,
M. Hiney, S. Davey, P.R. Smith, R. Powell, T. Barry and F. Gannon (1989) Studies on asymptomic infections of salmon with Aeromonas salmonicida. [Poster Presentation], 4th European Association of Fish Pathologists. Diseases of Fish and Shellfish, Santiago de Compostela, Spain , 25-SEP-89 - 27-SEP-89. [Details]
(1989) The Genetics Society,
Barry, T. (1989) Nucleic acid based eubacterial diagnostics - an emerging technology. [Oral Presentation], The Genetics Society, TCD, Dublin, ireland , 23-MAR-89 - 24-MAR-89. [Details]

Other Journals

  Year Publication
(1997) 'Educating and training microbiologists for the new millennium'
Barry, T. (1997) 'Educating and training microbiologists for the new millennium' The Irish Scientist, (60) :5-5. [Details]

Professional Associations

  Association Function From / To
INHALE: Potential of Molecular Diagnostics for Hospital-Acquired and Ventilator-Associated Pneumonia in UK Critical Care - A UK NIHR Programme Scientific Advisor 01-JAN-16 / 31-DEC-20
Dublin Institute of Technology, Dublin, Ireland Assessor for Programme Validation Panel BSc in Biomedical and Molecular Diagnostics 24-MAR-16 / 08-APR-16
SFI Workshop on Commercialisation - Invite only Expert /leading Irish academic with a track record in commercialisation 25-AUG-15 / 24-SEP-15

Patents

  Patent Number Title Granted
GR97401243T Generation of specific probes for target nucleotide sequences 01-JAN-99
S85514 Ace2 as a target gene for the molecular identification of yeast and fungal species 01-JAN-99
AU 5365290D Generation of specific probes for target nucleotide sequences 01-JAN-99
EPO395292B1 Generation of specific probes for target nucleotide sequences 01-JAN-99
MX283047 Nucleic acid probe-base diagnostic assays for prokaryotic and eukaryotic organisms 19-JAN-11
IE128789A Generation of specific probes for target nucleotide sequences 01-JAN-99
US7,972,777 Nucleic acid probe-base diagnostic assays for prokaryotic and eukaryotic organisms 01-JAN-99
DE69030131A Generation of specific probes for target nucleotide sequences 01-JAN-99
ZA90/2924 Nucleic acid probe-base diagnostic assays for prokaryotic and eukaryotic organisms 01-JAN-99
CN00807503.4 Nucleic acide probe-base diagnostic assays for prokaryotic and eukaryotic organisms 19-FEB-14
DE69030131T Generation of specific probes for target nucleotide sequences 01-JAN-99
2008/0487 SW15 gene as a diagnostic target for the identification of fungal and yeast species 16-JUL-15
AU2007331059 Mycoseq: Nucleic acid probes for detection of yeast and fungal species 09-JAN-14
EP1179090 Nucleic acid probe-base diagnostic assays for prokaryotic and eukaryotic organisms 01-JAN-99
ES90304164T Generation of specific probes for target nucleotide sequences 01-JAN-99
JP10185890A Generation of specific probes for target nucleotide sequences 01-JAN-99
ZA2010/09017 SW15 gene as a diagnostic target for the identification of fungal and yeast species 28-MAR-12
DK90304164T Generation of specific probes for target nucleotide sequences 01-JAN-99
AU2009256588 SW15 gene as a diagnostic target for the identification of fungal and yeast species 16-JUL-15
JP2009-540964 Mycoseq: Nucleic acid probes for detection of yeast and fungal species 02-JUN-15
AT90304164T Generation of specific probes for target nucleotide sequences 01-JAN-99
US1993/173639A Generation of specific probes for target nucleotide sequences 01-JAN-99
ZA9002924A Generation of specific probes for target nucleotide sequences 01-JAN-99
AU5365290A Generation of specific probes for target nucleotide sequences 01-JAN-99
ZA2009/03765 Nucleic acid probes for detection of yeast and fungal species 01-JAN-99
AU2004203283 Nucleic acid probe-base diagnostic assays for prokaryotic and eukaryotic organisms 01-JAN-99
S85506 P2/P2A/P2B gene sequences as diagnostic targets for the identification of fungal and yeast species 01-JAN-99
S85507 EIF2y gene as a diagnostic target for the identification of fungal and yeast species 01-JAN-99

Education

  Year Institution Qualification Subject
1992 UCD Master of Business Studies Business Studies
1990 UCG PhD Eukaryotic Molecular Biology

Community Engagement

  Title Type From / To
Outreach Focus on Respiratory 10-SEP-12 / 10-SEP-12
Outreach Ressearch team at NUIG are a key part of pneumonia diagnosis project 31-AUG-12 / 31-AUG-12
Teaching (e.g. Service learning / comunity based learning) Transition Year Secondary School Students 21-JAN-13 / 01-FEB-13
Outreach Organised Coffee Morning for Irish Guide Dogs for the Blind in Microbiology 01-JUN-12 / 01-JUN-12
Outreach NUIG Researchers and detection of Infectious diseases 05-SEP-12 / 05-SEP-12
Outreach EU pneumonia diaganosis project 10-SEP-12 / 10-SEP-12

Teaching Interests

I am interested in teaching all aspects of Microbiology from undergraduate to postgraduate level. More specifically I am interested in research led teaching in the area of infectious disease and antimicrobial resistance rapid novel nucleic acid in vitro amplification and sequencing based diagnostics.

Coordinator of 3rd Year Microbiology Degree Course



Current Postgraduate Students (Research)

  Student Degree Type Type
Helena Coughlan Doctorate - Structured PhD (Science) Supervisor

Modules Taught

  Term/Year Module Title Module Code Subject / Desc
Postgrad Dip in Applied Microbiology Semester II Diagnostics Technologies MI5105 Latest Devlopemnts in NAD
Masters in Biotechnology Semester II Diagnostic Biotechnology BG5105 Latest Devlopemnts in NAD
Third year Microbiology Semester I Microbial Genetics and Metabolic Systems MI326 Microbial Metabolism
Second year Microbiology Semester II Microbes and the Environment MI204 Basic Microbial Metabolism
Fourth year Microbiology Semester I Laboratory Projects MI405 Microbial Nucleic Acid Diagnostics
Fourth year Microbiology Semester II Dynamics of Microbial Gene Regulation MI440 The RNA World
Second year Microbiology Semester II Laboratory Skills in Microbiology MI203 Pre practical based lectures for this module
Third year Microbiology Semester II Skills for Research Practical Series MI325 Introduction to Research and Peer Reviewed Publishing
Fourth year Microbiology Semester I Problem Solving Paper MI413 Scientific Peer reviewed Paper Analysis