Dr Barry O'Brien

BEng, Dip Pr Mgt, MEng, Ph.D

Contact Details

Research Fellow
Mechanical & Biomed Engineering
NUI Galway

T: Ext. 4266
E: barry.obrien@nuigalway.ie
 
researcher

Biography

Barry graduated from University of Limerick in 1987 with a B.Eng in Materials Engineering and then worked as a project engineer at BHP Laboratories in Limerick until 1995. During this time he worked on materials research projects investigating aerospace alloys, engineering ceramics and medical device materials. He also completed an M.Eng in 1991 on lightweight alloys for satellite structures. Barry joined Boston Scientific in 1996, working in R&D on projects to develop materials and processes for a range of self-expanding devices and balloon-expanding stents. Subsequently he was Technical Team Leader on a number of medical device technology projects covering topics such as iridium oxide stent coatings, alternative stent materials and novel drug delivery concepts. Barry returned to university, completing a PhD in 2009, in the field of MRI-compatible implant materials. He has since worked as Principal Investigator and Project Manager on a number of medical device projects relating to biodegradable magnesium implants and peripheral vascular stents. Currently he is NUI Galway's project manager on an FP7 project that is developing a tissue-engineered tracheobronchial stent.

Research Interests

Novel medical devices and therapies
Medical device materials
In-vivo performance of devices and materials
Surface engineering
Biodegradable metals

Barry is an inventor on over 10 granted patents in the fields of medical devices and device materials & processes, as well as a further 10 published patents currently under reviiew.

Peer Reviewed Journals

  Year Publication
(2014) 'Strain-gradient modelling of grain size effects on fatigue of CoCr alloy'
Sweeney, CA,O'Brien, B,Dunne, FPE,McHugh, PE,Leen, SB (2014) 'Strain-gradient modelling of grain size effects on fatigue of CoCr alloy'. Acta Materialia, 78 :341-353 [DOI] [Details]
(2014) 'Experimental characterisation for micromechanical modelling of CoCr stent fatigue'
Sweeney, CA,O'Brien, B,McHugh, PE,Leen, SB (2014) 'Experimental characterisation for micromechanical modelling of CoCr stent fatigue'. Biomaterials, 35 :36-48 [DOI] [Details]
(2011) 'A corrosion model for bioabsorbable metallic stents'
Grogan, JA,O'Brien, BJ,Leen, SB,McHugh, PE (2011) 'A corrosion model for bioabsorbable metallic stents'. Acta Biomaterialia, 7 :3523-3533 [DOI] [Details]
(2009) 'The evolution of cardiovascular stent materials and surfaces in response to clinical drivers: A review'
O'Brien, B.,Carroll, W. (2009) 'The evolution of cardiovascular stent materials and surfaces in response to clinical drivers: A review'. Acta Biomaterialia, 5 (44):945-958 [Details]
(2008) 'Development of a new niobium-based alloy for vascular stent application'
O'Brien, B. (2008) 'Development of a new niobium-based alloy for vascular stent application'. Journal of Mechanical Behavior of Biomedical Materials, 1 :303-312 [Details]
(2008) 'Characterization of an NbTaWZr alloy designed for magnetic resonance angiography compatible stents'
O'Brien, BJ,Stinson, JS,Boismier, DA,Carroll, WM (2008) 'Characterization of an NbTaWZr alloy designed for magnetic resonance angiography compatible stents'. Biomaterials, 29 :4540-4545 [DOI] [Details]
(2008) 'Development of a new niobium-based alloy for vascular stent applications'
O'Brien, B,Stinson, J,Carroll, W (2008) 'Development of a new niobium-based alloy for vascular stent applications'. Journal Of The Mechanical Behavior Of Biomedical Materials, 1 :303-312 [DOI] [Details]
(2008) 'Initial exploration of Ti-Ta, Ti-Ta-Ir and Ti-Ir alloys: Candidate materials for coronary stents'
O'Brien, B,Stinson, J,Carroll, W (2008) 'Initial exploration of Ti-Ta, Ti-Ta-Ir and Ti-Ir alloys: Candidate materials for coronary stents'. Acta Biomaterialia, 4 :1553-1559 [DOI] [Details]
(2002) 'Passivation of nitinol wire for vascular implants - a demonstration of the benefits'
O'Brien, B,Carroll, WM,Kelly, MJ (2002) 'Passivation of nitinol wire for vascular implants - a demonstration of the benefits'. Biomaterials, 23 :1739-1748 [DOI] [Details]

Book Chapters

  Year Publication
(2011) 'Shape Memory Alloys for use in Medicine'
O'Brien, B. (2011) 'Shape Memory Alloys for use in Medicine' In: Comprehensive Biomaterials. Elsevier. [Details]

Conference Publications

  Year Publication
(2004) Materials & Processes for Medical Devices
Barry O'Brien, Chandru Chandrasekaren (2004) Development of Iridium Oxide as a Cardiovascular Stent Coating Materials & Processes for Medical Devices [Details]
(1999) First European Conference on Shape Memory and Superelastic Technologies
Barry O'Brien (1999) Application of NiTi in minimally invasive medical devices - an overview from a device manufacturer First European Conference on Shape Memory and Superelastic Technologies [Details]

Reviews

  Year Publication
(2009) The evolution of cardiovascular stent materials and surfaces in response to clinical drivers: A review.
O'Brien, B,Carroll, W (2009) The evolution of cardiovascular stent materials and surfaces in response to clinical drivers: A review. Reviews [DOI] [Details]

Professional Associations

  Association Function From / To
Project Management Institute Member /
Biomedical Engineering Society (BMES) Member /
American Society for Materials (ASM) Member /

Teaching Interests

ME326 Metals & Metal Processing (2013-14, 2012-13, 2011-12, 2010-11)
BME401 Biomedical Engineering Final Year Project (2014-15, 2013-14)